CTRI/2022/01/039527招募中未知
Acute Hemodynamic Response to Carvedilol in Predicting Survival in Acute on Chronic Liver Failure Patients - A Pilot Study
试验速览
- 阶段
- 未知
- 状态
- 招募中
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •1) Patients of ACLF (APASL criteria) - jaundice (serum bilirubin ââ?°Â¥ 5 mg/dL and coagulopathy (INR ââ?°Â¥ 1.5) complicated within 4 weeks by clinical ascites and/or encephalopathy in a patient with previously diagnosed or undiagnosed chronic liver disease/cirrhosis.
- •2) Age 18-70 yrs
- •3) Baseline HVPG ââ?°Â¥ 12 mmHg.
排除标准
- •1) Contraindications to NSBB (heart rate < 65 /min, BP < 110/65 mm Hg, asthma, heart failure),
- •2) Portal Vein Thrombosis,
- •3) Hepatocellular carcinoma,
- •5) HE grades 2-4,
- •6) NSBB therapy within 5 days,
- •7) Pregnancy,
- •8) Lactation,
- •9) Planned for LT in the next 12 weeks
- •10) No consent.
研究者
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