Cohort of Patients Naive of Antiretroviral Treatment at Enrollment
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 800
- 试验地点
- 1
- 主要终点
- Patients prognosis at short, medium and long term
研究概览
简要总结
The purpose of this study is to evaluate the short, medium and long-term prognosis for newly diagnosed HIV patients.
详细描述
The purpose of this study is to evaluate the short, medium and long-term prognosis for newly diagnosed HIV patients.
This study aims to precise the impact of HIV infection treatment on morbidity and mortality, the factors related to treatment response, clinical and biological complications, their consequences, especially lipodystrophy and metabolic abnormalities, associated factors especially genetic, aspects linked to aging.
In addition, the study describes the evolution of patients living conditions and behaviors remotely from their screening, particularly related to sexuality, reproduction, and health inequalities and to study the long-term treatment adherence.
One third of the patients were included in the metabolic disorders module. This module includes additional biological and imaging explorations.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 15 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients infected with HIV-1, with a recent diagnosis (<1 year before enrollment)
- •Untreated at the time of enrollment,
- •Aged 15 or more
- •Agreeing to participate in the cohort.
排除标准
- •Under protection(saving) of justice
结局指标
主要结局
Patients prognosis at short, medium and long term
时间窗: Up to 12 years
次要结局
- Antiretroviral treatment impact(Up to 12 years)
- Aging population(up to 12 years)
- Impact of inflammatory markers on antiretroviral treatment(Up to 12 years)
- Socio-economic conditions (sexuality, education, reproduction, health inequalities)(Up to 12 years)