Evaluation of the Risk Factors Influencing the Prognosis of Elderly Patients With Acute Poisoning.
试验速览
- 阶段
- 不适用
- 入组人数
- 20
- 主要终点
- Change in Acute physiology and chronic health evaluation II score (APACHE II) in cases of elderly patients with acute poisoning.
研究概览
简要总结
Acute poisoning is a major public health problem all over the world, it causes significant mortality and morbidity. It primarily involves younger populations, with less than 3% of the affected cases being in people aged 60 years or older in most studies. More than half of the intoxication events in the elderly over 65 years old were accidental.
详细描述
The elderly are different from younger adults in many aspects. There are age related physiological changes. They have a higher incidence of comorbidities and use of many medications for chronic conditions, both of which make the elderly more susceptible to acute poisoning and its related consequences.
Although the elderly form a relatively small proportion of those admitted to hospital for acute self-poisoning, the poisoning in them is often more serious, complications are more frequent and a fatal outcome is more common.
The presence of multiple physical, social, and psychiatric problems, with possible difficulties in the diagnosis of poisoning make the management of the elderly more complicated than that of younger poisoned patients. There are three main difficulties in diagnosing acute poisoning in the elderly. At first, it may not be easily obvious that the patient has taken an overdose. Secondly, the presence of pre-existing diseases may obscure the clinical picture and finally, the drug may cause physical signs that similar to common problems of old age.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 60 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •all patients more than 60 years will be included.
排除标准
- •younger than 60 years.
结局指标
主要结局
Change in Acute physiology and chronic health evaluation II score (APACHE II) in cases of elderly patients with acute poisoning.
时间窗: 24 hours after admission to intensive care unit (ICU).
"Acute Physiology And Chronic Health Evaluation II(APACHE II) " is a severity-of-disease classification system. one of several ICU scoring systems. It is applied within 24 hours of admission of a patient to an intensive care unit (ICU): an integer score from 0 to 71 is computed based on several measurements; higher scores correspond to more severe disease and a higher risk of death.
Change in Poisoning Severity Score (PSS) in cases of elderly patients with acute poisoning.
时间窗: 24 hours after admission to intensive care unit (ICU).
"Poisoning Severity Score (PSS)" is a standardized scale for grading the severity of poisoning allows qualitative evaluation of. morbidity caused by poisoning, better identification of real risks and comparability of data.
次要结局
未报告次要终点
研究者
Abeer hussien Mohamed
Teaching assistant in Forensic Medicine &Clinical Toxicology Department Faculty of Medicine
Sohag University