NCT00039507已完成2 期
Pilot Study: Radiofrequency Ablation Of Resectable Non-Small Cell Lung Cancer
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 试验地点
- 1
研究概览
简要总结
RATIONALE: Radiofrequency ablation uses high-frequency electric current to kill tumor cells. Combining radiofrequency ablation with surgery may kill more tumor cells.
PURPOSE: Phase II trial to study the effectiveness of combining radiofrequency ablation with surgery in treating patients who have stage I or stage II non-small cell lung cancer.
详细描述
OBJECTIVES:
- Determine the acute effects of intraoperative radiofrequency tumor ablation (RFA) in patients with resectable non-small cell lung cancer.
- Determine the treatment-related toxicity in patients treated with this therapy.
- Determine the dimensions of the RFA lesion produced by the ablation procedure in these patients.
OUTLINE: Patients undergo intraoperative radiofrequency tumor ablation over 10-15 minutes for each tumor immediately followed by tumor resection.
PROJECTED ACCRUAL: A maximum of 20 patients will be accrued for this study.
研究设计
- 研究类型
- Interventional
- 主要目的
- Treatment
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •DISEASE CHARACTERISTICS:
- •Diagnosis of malignant non-small cell lung cancer (NSCLC)
- •Intraoperative needle biopsy confirmation allowed
- •Resectable disease (stage I or II)
- •All tissue to be treated by radiofrequency tumor ablation must be completely contained within boundaries of planned lung resection
- •Medically fit to undergo lung resection
- •PATIENT CHARACTERISTICS:
- •Performance status:
- •Not specified
- •Life expectancy:
- •Not specified
- •Hematopoietic:
- •Not specified
- •Not specified
- •Not specified
- •Not pregnant or nursing
- •PRIOR CONCURRENT THERAPY:
- •Biologic therapy:
- •No prior or concurrent biologic therapy
- •Chemotherapy:
- •No prior or concurrent chemotherapy
- •Endocrine therapy:
- •No prior or concurrent endocrine therapy
- •Radiotherapy:
- •No prior or concurrent radiotherapy
- •See Disease Characteristics
- •No other prior therapy for NSCLC
排除标准
- 未提供
研究者
研究点 (1)
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