NL-OMON45428已完成不适用
Changes in the respiratory microbial and biochemical environment after the start of CFTR targeted treatment in patients with cystic fibrosis - Microbiome changes after CFTR targeted therapy
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Patients with a (predominant) class II mutation (almost exclusively homozygous Phe508del) for cystic fibrosis (N<=20) who will be started on Ivacaftor/Lumacaftor (CFTR targeted therapy; Orkambi) therapy will be included in this longitudinal observational study.
排除标准
- •For the bronchoscopy (part of the research protocol) the following patients will be excluded:
- •* Pre-lung transplant trajectory
- •* No informed consent for the procedure
- •* Deemed inappropriate by the treating physician.
研究者
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