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临床试验/NCT04868929
NCT04868929已完成不适用

The Brain Activation During Motor Execution, Motor Imagery, Action Observation, and Mirror Visual Feedback in Healthy Adults

National Taiwan University Hospital1 个研究点 分布在 1 个国家目标入组 43 人开始时间: 2021年5月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
43
试验地点
1
主要终点
Brain activities over primary motor cortex

研究概览

简要总结

This study aims to investigate the brain activation during different motor patterns, including motor execution (ME), motor imagery (MI), action observation (AO) and mirror visual feedback (MVF). In addition, the relations between brain activation and motor performance will also be explored. This study includes two parts, which are upper limb and lower limb part. While executing all the tasks, brain activation in primary motor cortex(M1), premotor cortex(PMC), and supplementary motor cortex(SMA) will be monitored by functional near-infrared spectroscopy. One-way ANOVA with repeated measure will be used to detect the differences of brain activation level between each mode. Pearson correlation coefficient will be used to determine the relations of brain activation and motor performance.

详细描述

In upper limb part, subjects will be instructed to execute functional reaching task in ME, MI, AO, and MVF mode. During ME mode, motor performance including maximum speed, maximum acceleration, and jerk will be collected simultaneously. In the lower limb part, subjects will be instructed to walking over ground in ME, MI, and AO mode. During ME mode, the temporal and spatial gait parameters, including speed, stride time, cadence, and stride length will be collected.

研究设计

研究类型
Observational
观察模型
Case Crossover
时间视角
Cross Sectional

入排标准

年龄范围
20 Years 至 30 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • 未提供

排除标准

  • 未提供

结局指标

主要结局

Brain activities over primary motor cortex

时间窗: Day 1

A multichannel wearable fNIRS imaging system (NIRSport2, NIRx Medical Technologies LLC, Glen Head, NY, USA) is used to detect the hemodynamics.

Brain activities over premotor cortex

时间窗: Day 1

A multichannel wearable fNIRS imaging system (NIRSport2, NIRx Medical Technologies LLC, Glen Head, NY, USA) is used to detect the hemodynamics.

Brain activities over supplementary motor area

时间窗: Day 1

A multichannel wearable fNIRS imaging system (NIRSport2, NIRx Medical Technologies LLC, Glen Head, NY, USA) is used to detect the hemodynamics.

次要结局

  • Motor performance of upper limb -maximum speed(Day 1)
  • Motor performance of lower limb - gait speed(Day 1)
  • Motor performance of lower limb - cadence(Day 1)
  • Motor performance of lower limb - stride length(Day 1)
  • Motor performance of upper limb -maximum acceleration(Day 1)
  • Motor performance of upper limb - jerk(Day 1)
  • Motor performance of lower limb - stride time(Day 1)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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