Objective Verification of Physiologic Changes During Accommodation Under Binocular, Monocular, and Pinhole Conditions
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 64
- 主要终点
- Accommodative power
研究概览
简要总结
The investigators believe that this simple, clear, and objective study may be a great help in understanding the accommodative response during various accommodative stimulation conditions.
详细描述
The purpose in this study was to investigate physiological changes in accommodative power, pupil diameter, astigmatic value, and axis when visual stimuli were applied under binocular, monocular (dominant eye, non-dominant eye, ipsilateral, and contralateral), and pinhole conditions using the WAM-5500 binocular autorefractor/keratometer (Grand Seiko Co. Ltd., Hiroshima, Japan).
研究设计
- 研究类型
- Observational
- 观察模型
- Case Crossover
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •age between 20 and 40 years
- •spherical equivalent (SE) within ± 4.0 diopters (D)
- •correctable distant and near visual acuity by glasses to 20/20
- •normal ocular alignment.
排除标准
- •disturbance of accommodation (e.g., Adie's pupil, Parkinson's disease, accommodative esotropia, accommodative spasm, presbyopia)
- •disorders that can affect accommodation (e.g., history of ocular trauma, previous ocular surgery)
- •disorders that might limit testing accuracy (e.g., corneal pathological features, cataract, glaucoma, vitreous opacity, and retinal abnormalities).
结局指标
主要结局
Accommodative power
时间窗: Subjects performed this examination while being under binocular, monocular, and pinhole conditions with one week apart in random order after baseline study
Accommodative powers in diopters were measured using WAM-5500 binocular autorefractor/keratometer
Pupil diameter
时间窗: Subjects performed this examination while being under binocular, monocular, and pinhole conditions with one week apart in random order after baseline study
Pupil diameters in millimeters were measured using WAM-5500 binocular autorefractor/keratometer
Astigmatic value and axis change
时间窗: Subjects performed this examination while being under binocular, monocular, and pinhole conditions with one week apart in random order after baseline study
Astigamtic value in diopters and axis change in degrees were measured using WAM-5500 binocular autorefractor/keratometer The spherical equivalent (sphere + 1/2 cylinder) was used to assess the response to refractive stimuli. The principal meridian of the cylinder for 0.25D refractive stimulus was set to the baseline axis. For 2D, 3D, and 4D refractive stimuli, vertical movement was determined when the baseline meridian moved to the 90' axis, and it was considered horizontal movement when it moved to the 0' or 180' axis.
次要结局
未报告次要终点
研究者
Hong Hyun Park
Resident
Chung-Ang University Hosptial, Chung-Ang University College of Medicine