临床试验/NCT01886664

NCT01886664已完成4 期

Comparison of PRS According to Inhalation Agent During LDLT

Seoul National University Hospital1 个研究点分布在 1 个国家目标入组 70 人开始时间: 2012年12月最近更新: 2014年6月26日

适应症

干预措施

试验速览

阶段: 4 期
状态: 已完成
发起方: Seoul National University Hospital
入组人数: 70
试验地点: 1
主要终点: frequency of PRS

研究概览研究设计入排标准研究组 & 干预措施结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

The investigators tried to evaluate the effect of desflurane on the incidence of postreperfusion syndrome during living donor liver transplantation surgery. The investigators used sevoflurane as a comparison.

研究设计

研究类型: Interventional
分配方式: Randomized
干预模型: Parallel
主要目的: Prevention
盲法: Single (Participant)

入排标准

年龄范围: 18 Years 至 65 Years（Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•elective LDLT

排除标准

•age < 18, age > 65
•patient refusal
•re-transplantation

研究组 & 干预措施

Sevoflurane

Active Comparator

Performing liver transplantation under general anesthesia using sevoflurane

干预措施: sevoflurane (Drug)

Desflurane

Experimental

Performing liver transplantation under general anesthesia using desflurane

干预措施: Desflurane (Drug)

结局指标

主要结局

frequency of PRS

时间窗: immediately after reperfusion

reperfusion syndrome occurs, if it occurs, immediately after reperfusion. Therefore, the primary outcome, reperfusion syndrome, can only be assessed immediately after reperfusion.

次要结局

ICU length of stay(after LT until the patient is transferred to the ward)

研究者

发起方

Seoul National University Hospital

申办方类型

Other

责任方

Sponsor

研究点 (1)

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