Analysis of Motor Skills in Subjects Aged 55 and Over: the Role of Cognitive Abilities for Planning Movement.
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 684
- 试验地点
- 1
- 主要终点
- Sequence 1: symmetry ratio of the finger speed profile
研究概览
简要总结
Falling is an event that is more frequent and severe in older age. It can lead to a loss of autonomy and a decrease in quality of life. It is therefore important to understand this phenomenon in order to better prevent it. Among the multiple risk factors associated with falling, recent research has shown a link between the decline in cognitive abilities (i.e., the mental processes that form our knowledge, such as memory) and the risk of falling. However, the impact of this cognitive decline on motor skills is still poorly understood. The purpose of this research is to study how the changes induced by aging affect motor skills. This would make it possible to take a new look at the phenomenon of falls occurring in the elderly and, in the long term, to improve the prevention and rehabilitation.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Neurotypical subjects group:
- •Person aged 18 to 40 years
- •Person who has given oral consent
- •Affiliated to national health insurance
- •Right-handed person
- •Group of elderly neurotypical subjects:
- •Person over 55 years of age
- •Person who has given oral consent
- •Affiliated to national health insurance
- •No cognitive problems (MMSE score >26)
- •Right-handed person
- •Elderly mild cognitive disorder subject group:
- •Person over 55 years of age
- •Person who has given oral consent
- •Diagnosis of Mild Cognitive Disorder made by a neurologist at the Centre Mémoire Ressources et Recherche (CMRR) of the University Hospital of Dijon, following the recommendations of the National Institute for Aging and Alzheimer's Association (Albert et al., 2011) This diagnosis is based on psychometric tests, brain imaging and the evolution of cognitive disorders, including an MMSE test.
- •Right-handed person
排除标准
- •Neurological or psychiatric history with the exception of the TCL group.
- •Follow-up of drug treatment in the last three months that may affect cognitive and/or motor skills.
- •Received a shoulder prosthesis on the dominant side.
- •Received a hip and/or knee replacement less than a year ago.
- •Disabling joint disease of the hip or knee shoulder
- •Protected adults (curatorship, guardianship)
- •Person deprived of their liberty b judicial or administrative decision
- •Pregnant, parturient or breastfeeding woman
- •Major unable to consent
结局指标
主要结局
Sequence 1: symmetry ratio of the finger speed profile
时间窗: through study completion, an average of 3 years
Sequence 2 : perception bias (error in degrees of angle) of dynamic subjective visual vericality
时间窗: through study completion, an average of 3 years
Sequence 3 : activation time of the focal muscles in relation to the postural muscles
时间窗: through study completion, an average of 3 years
次要结局
未报告次要终点