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临床试验/NCT00001366
NCT00001366已完成不适用

MRI-Based Functional Language Mapping in Children With Epilepsy

National Institute of Neurological Disorders and Stroke (NINDS)1 个研究点 分布在 1 个国家目标入组 230 人开始时间: 1993年8月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
230
试验地点
1

研究概览

简要总结

Researchers are interested in studying if magnetic resonance imaging (MRI) is practical for locating the areas of the brain associated with language in children with epilepsy.

When a region of the brain is active, it uses more fuel in the form of oxygen and sugar (glucose). As the brain uses more fuel it produces more waste products, carbon dioxide and water. Blood carries fuel to the brain and waste products away from the brain. As brain activity increases blood flow to and from the area of activity increases also.

Patients participating in the study will be asked to perform tasks designed to test language skills while undergoing an MRI to detect areas of the brain using oxygen and receiving blood flow.

详细描述

We propose to study the feasibility of utilizing MRI to perform functional mapping of language cortex in children with epilepsy. We will use 1.5 Tesla MRI to study cerebral blood flow and tissue oxygenation during cognitive activation tasks derived from previous adult studies.

研究设计

研究类型
Observational

入排标准

性别
All
接受健康志愿者

入选标准

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排除标准

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研究者

研究点 (1)

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