Effect of Transcutaneous Electrical Acupoint Stimulation(TEAS) on the Incidence of Hypotension After Spinal Anesthesia in Patients Undergoing Cesarean Section: a Prospective, Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 150
- 试验地点
- 2
- 主要终点
- Incidence of hypotension
研究概览
简要总结
The purpose of this study is to compare the effect of TEAS on hypotension after spinal anesthesia in patients undergoing cesarean section
详细描述
Patients were randomly assigned to 3 groups, receiving TEAS , non-acupoint stimulation or no-stimulation after spinal anesthesia respectively. 1.4 ml of bupivacaine mixed with 0.2ml of 50% glucose was given for spinal anesthesia under lateral position. Then the patient was switched to supine position and the OR table was tilted to the left for 15 degree. The sensory loss level was assessed. The blood pressure and heart rate every 2min were recorded for 30min after spinal anesthesia. The adverse events and use of ephedrine adverse events were recorded as well.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Age>18yrs
- •American Society of Anesthesiologists(ASA) status 1-2
- •Scheduled for elective cesarean under spinal anesthesia
- •Gestational age>38weeks, singleton pregnancy
- •Informed consented
排除标准
- •Patients with pre-eclampsia or diabetes
- •Patients with hypertension or cardiac dysfunction
- •Disturbance of communication
- •Placental abruption
结局指标
主要结局
Incidence of hypotension
时间窗: During 30min after spinal anesthesia
次要结局
- Average systemic blood pressure(SBP) and diastolic blood pressure(DBP)(During 30min after spinal anesthesia)
- Lowest SBP and DBP(During 30min after spinal anesthesia)
- Dosage of ephedrine(During 30min after spinal anesthesia)
- postoperative nausea and vomiting(PONV) score(During 30min after spinal anesthesia)
- Incidence of dizzy and dyspnea(During 30min after spinal anesthesia)
- Change of concentration of serum adrenaline and noradrenaline(Immediately after TEAS)
研究者
wangqiang
Professor
Xijing Hospital