Comparison of Magnesium sulphate and Dexamethasone as adjuvants to Ropivacaine in ultrasound guided brachial plexus block for postoperative analgesia in patients undergoing upperlimb surgeries A randomised controlled trial
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- To compare the duration of postoperative analgesia of ropivacaine and magnesium sulphate with ropivacaine and dexamethasone in brachial plexus blocks using numerical rating scale(NRS) for patients undergoing elective upper limb surgeries under general anaesthesia.
研究概览
简要总结
To compare the duration of postoperative analgesia with 0.75% ropivacaine (20ml) and magnesium sulphate 250mg (1ml) versus 0.75%ropivacaine (20ml)and dexamethasone 4mg (1ml) in ultrasound guided brachial plexus blocks in patients undergoing elective upper limb surgeries under general anaesthesia and to compare the pain score and total requirement of analgesics over 24 hours postoperatively. Duration of analgesia will be calculated from the time of administration of the block to the time of rescue analgesia. Pain score will be calculated with the help of numerical rating scale (NRS) and when the patient has a pain score >/=3, analgesic will be started with paracetamol at a dose of 15mg/kg 8th hourly. Pain score will be assessed every 4th hourly. If the pain does not subside, tramadol 100mg will be added and at the end of 24 hours total analgesic requirement is calculated
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- All
入选标准
- •Age: 18 -70 years
- •ASA physical status I and II patients
- •Body mass index (BMI) of 18-30 kg/m2
- •Patients undergoing elective upper limb surgeries under general anaesthesia with brachial plexus block.
排除标准
- •Patient Refusal
- •Allergy to local anesthetic
- •Altered coagulation profile
- •Infection at site of injection
- •Failure of block.
结局指标
主要结局
To compare the duration of postoperative analgesia of ropivacaine and magnesium sulphate with ropivacaine and dexamethasone in brachial plexus blocks using numerical rating scale(NRS) for patients undergoing elective upper limb surgeries under general anaesthesia.
时间窗: Patient will be assessed for postoperative analgesia using numerical rating scale every 4th hourly for 24 hours
次要结局
- To compare the total requirement of analgesics over 24 hour period postoperatively in patients undergoing upper limb surgeries under general anaesthesia with brachial plexus block using magnesium sulphate & dexamethasone as adjuvants to ropivacaine(Every 4th hourly for 24 hours)
- To compare the pain score at 4 hour intervals postoperatively in patients undergoing elective upper limb surgeries under general anaesthesia with brachial plexus block using magnesium sulphate & dexamethasone as adjuvants to ropivacaine(Every 4th hourly for 24 hours)
- To compare the various hemodynamic parameters in patients undergoing elective upper limb surgeries under general anaesthesia with brachial plexus block using magnesium sulphate & dexamethasone as adjuvants to ropivacaine(Every 4th hourly for 24 hours)
研究者
Jishina Issac
MOSC medical college kolenchery