VItamin D treatment Effect on retinal nerve fiber loss after Optic neuritis - VIDEO-trial

Erasmus Medical Center0 个研究点开始时间: 2010年3月16日最近更新: 2012年3月19日

适应症

试验速览

暂无简介。

•Patients fulfilling the following criteria are included:
•- Single unilateral optic neurits (ON)
•- Age between 18 and 50 year
•- Neuro-ophtalmological examination within 4 weeks of symptom onset
•Clinically confirmed ON is defined as fulfilling at least 4 of 5 of following criteria: pain with eye movement, sub-acute onset of decreased Snellen acuity, color vision loss, a relative afferent pupillary defect, and compatible fundus examination (i.e. mild or no optic edema and the absence of pallor at the time of the acute event).
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range
•F.1.3 Elderly (>=65 years) no
•F.1.3.1 Number of subjects for this age range

•Patients are excluded who:
•- Have prior known ON, MS or prior symptoms suggestive of demyelination;
•- Have other suspected or established causes of vision loss (e.g. glaucoma, amblyopia);
•- Are unable to undergo OCT testing;
•- Use more than 1 vitamin supplement;
•- Have used immunomodulatory therapy (e.g. interferone) in the 3 months prior to inclusion;
•- Have had methylprednisolone treatment in the 3 months prior to inclusion;
•- Have an allergy to peanuts.

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