A study of vitamin D efficacy on neuropathy in diabetic patients

Not Applicable

• Conditions: Diabetic neuropathy.; Diabetic Polyneuropathy; G 63.2*

• Registration Number: IRCT2013082014416N1
• Lead Sponsor: Kermanshah Univesity Of Medical Science,Research vice-presidency

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

patients with diabetes mellitus; both genders; under anti hyperglycemic agents therapy; with diabetic peripheral neuropathy syptoms in the form of pain and paresthesia in rest for at least 1 month and have vitimin D deficiency (<30 ng/ml) and no drug history of vitimin D in one year ago. Neuropathy score in diabetic patients is based on TCSS criteria(6-19 scores)
Exclusion criteria: no consent or ability to participate in the study; drug history of calcium or omega; supplements in 3 last months; drug history of effective drugs in vitimin D metabolism (estrogen, calcitonin...); history of diseases can change vitimin D metabolism(renal and liver diseases, cancers or other endocrine disorders); other etiologies of neuropathy (renal impairment or Cr>2g/dl or GBS) or in examination have radiculopathy; use of other drugs to relief painful neuropathy such as TCA antidepressants, Gabapentin, pergabalin in 3 last months.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Severity of diabetic neuropathy. Timepoint: First day,3 months later(90th day). Method of measurement: Toronto Clinical Score System(TCSS).