A Prediction Model of 28-day Mortality in Septic Shock
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 530
- 试验地点
- 1
- 主要终点
- All causes of 28 days mortality
研究概览
简要总结
This clinical study adopts the design of cohort research, selects the sepsis shock patients admitted to our hospital ICU as the research object, takes the 28-day mortality rate as the outcome index, collects the baseline data of the patient, the severity of the disease, vital signs, the main infection site, the laboratory-related index, the treatment method and other data, screens out the risk factors affecting the sepsis shock 28-day mortality rate and constructs the prediction model accordingly, analyzes the prediction model with the subject's working characteristic curve (ROC). The recognition ability of the model is calculated by the area under the ROC curve (AUC) and the ability of the model to predict 28-day mortality with SOFA and APACHE II.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age ≥ 18 years of age, gender-neutral;
- •Diagnosed with sepsis shock;
- •ICU survives longer than 48 h;
- •The preservation of clinical data is complete;
排除标准
- •Diagnosed with sepsis shock within 6 hours of emergency treatment; Combined with people with autoimmune diseases;
- •Organ transplantation or immunosuppressive treatment;
- •Severe heart, liver and kidney insufficiency;
- •Late stage of malignant tumor;
- •Referral or referral to another hospital;
结局指标
主要结局
All causes of 28 days mortality
时间窗: 28 days
The all-cause mortality rate is measured from the time the ICU is admitted to the hospital and 28 days after admission (regardless of ICU, hospitalization or out-of-hospital mortality).
次要结局
- ICU hospitalization time(2 years)
- hospitalization mortality(2 years)