Prevalence of Keratoconus in Inflammatory Bowel Diseases
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 201
- 主要终点
- Absence or presence of keratoconus in IBD patients
研究概览
简要总结
A retrospective study has shown the association between the inflammatory bowel diseases (IBD) and the presence of a keratoconus. This new study will measure the prevalence of keratoconus and follow its activity in patients affected by IBD and followed up in hepatology-gastroenterology department at Nancy Hospital. The prevalence of keratoconus will be compared to known data of literature about general population.
The secondary purpose is to search for a relationship between the presence of a keratoconus and activity criteria of IBD.
Perspectives are a systematic screening for keratoconus in patients affected by IBD with the amelioration of the ophthalmologic care of IBD patients and confirmation of the recent hypothesis of inflammatory origin of keratoconus.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Informed consent
- •Affiliation to social security plan
- •Diagnosis of IBD since more than 3 years, under treatment or not
排除标准
- •Protected person
- •Pregnant or breastfeeding women
- •Person in life-and-death emergency
- •Person deprived of liberty
- •Refusal to remove contact lenses, where necessary
研究组 & 干预措施
Keratoconus and IBD
Opthalmologic measure with DM OPD scan III (Nidek)
干预措施: Opthalmologic measure with DM OPD scan III (Nidek) (Device)
结局指标
主要结局
Absence or presence of keratoconus in IBD patients
时间窗: day 0
Data from OPD scan III corneal analyzer according to Rabinowitz and Klyce Maeda criteria. The presence of a keratoconus in at least one eye is considered positive.
次要结局
- IBD clinical features using the Montreal classification for IBD(day 0)