NCT05183880撤回不适用
Investigating the Oral Bioavailability of Vitamin C Administered Using Phosphycell™ Technology - a Phosphatidylcholine-lipid Encapsulation Technology.
适应症
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 2
- 主要终点
- Skeletal muscle vitamin C concentrations
研究概览
简要总结
The purpose of this study is to determine if crystalline vitamin C supplementation can acutely increase skeletal muscle vitamin C concentrations and if this can be potentiated by administering vitamin C using Phosphycell™ Technology - a phosphatidylcholine-lipid encapsulation technology.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Body mass index (BMI) 18.5 - 30 kg/m2
- •Age 18 - 40
- •Non-smoker
排除标准
- •Body mass index (BMI) < 18.5 or > 30 kg/m2
- •Age < 18 or > 40
- •Cardiovascular disease
- •Hypertension (≥ 140/90 mmHg)
- •Metabolic disease
- •Medications known to affect vitamin C metabolism
- •A known vitamin C deficiency
- •Less than 2 hours per week of physical activity or following a structured exercise training program.
- •Routine use of vitamin supplements
结局指标
主要结局
Skeletal muscle vitamin C concentrations
时间窗: 12 hours after vitamin C ingestion
Skeletal muscle vitamin C concentrations 12 hours after vitamin C ingestion will be measured using HPLC and compared to baseline and 6 hours after vitamin C ingestion
次要结局
- White blood cell vitamin C concentrations(24 hours after vitamin C ingestion)
- Cardiovascular function(24 hours after vitamin C ingestion)
- Blood plasma vitamin C concentrations(24 hours after vitamin C ingestion)
研究者
研究点 (2)
Loading locations...
相似试验
招募中
3 期
The effect of vitamin C in the treatment of pneumoniaIRCT20101106005114N3Mashhad University of Medical Sciences100
招募中
3 期
Evaluating the effectiveness of vitamin C intake in patients diagnosed with rotator cuff tears undergoing arthroscopic treatmentRotator Cuff tear.IRCT20231021059783N1Kerman University of Medical Sciences131
终止
2 期
High Dose Vitamin C in the Critically Ill PatientShockNCT01587963Rutgers, The State University of New Jersey11
尚未招募
不适用
The effect of vitamin C supplementation in the last month of pregnancy on neonatal bilirubin levelIRCT20091114002709N47Iran University of Medical Sciences144
已完成
1 期
Effects of Vitamin C Administration on Extravascular Lung Water in Patients With Severe Features of PreeclampsiaPreeclampsia SeverePreeclampsia PostpartumNCT03451266University Medical Centre Ljubljana34