A PET study of dopamine function in healthy subjects with hallucinations - dopamine function in healthy subjects with hallucinations

niversitair Medisch Centrum Utrecht0 个研究点目标入组 20 人开始时间: 待定最近更新: 2024年5月6日

适应症

试验速览

暂无简介。

•Physically healthy subjects, evaluated by medical history, physical examination and screening laboratory tests
•Experiences hallucinations with a frequency of at least once a week.
•Total SPQ score lower than 25
•No diagnosis on axis I or II based on DSM -IV criteria, confirmed by the CASH and the SCID II interview.
•Age between 18-60

•Use of psychotropic medication within four weeks before the scanning
•Drug or alcohol-abuse over a period of three weeks prior to the experiment. More then 15 cigarettes and more then 6 cups of caffeine containing coffee, cola or tea.
•A history of neurological illness or other medical problems potentially having central nervous system sequellae.
•Pregnancy, breast feeding and use of inadequate anti-conception.
•Use of other medication potentially influencing cerebral blood flow.
•Claustrophobia
•Exposure to radioactivity leading to yearly cumulative dose of 10 mSv or more
•Metal objects in or around the body (braces, pacemaker, metal fragments);
•Exposure to radioactivity leading to a yearly cumulative dose of 10 mSv or more.

发起方

niversitair Medisch Centrum Utrecht