NCT06379204已完成不适用
A Study on the Intervention of Metabolic Syndrome Patients With Exercise Prescription Based on Ventilatory Threshold Using Cardiopulmonary Exercise Test
Taiyuan Central Hospital of Shanxi Medical University1 个研究点 分布在 1 个国家目标入组 52 人开始时间: 2022年11月4日最近更新:
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 52
- 试验地点
- 1
- 主要终点
- Peak oxygen uptake
研究概览
简要总结
Analyze the clinical intervention effects and differences of progressive precision exercise prescriptions formulated by two methods for determining exercise intensity on metabolic syndrome (MS). Compare the effects of the two on the cardiovascular endurance of the MS population and verify the effectiveness of individualized methods in reducing absolute exercise intensity for MS patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 25 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients were included who met the Chinese Diabetic Society diagnostic criteria for MS-i.e., three or more of the following five items: (i) abdominal obesity (i.e., central obesity) with waist circumference ≥ 90 cm in males and ≥ 85 cm in females; (ii) hyperglycemia defined as fasting blood glucose ≥ 6.1 mmol/L or blood glucose ≥ 7.8 mmol/L two hours after glucose loading, or diagnosis of diabetes mellitus; (iii) hypertension defined as blood pressure ≥ 130/85 mmHg or diagnosed with hypertension; (iv) fasting triglycerides (TG) ≥ 1.70 mmol/L; and (v) fasting high-density lipoprotein cholesterol (HDL-C) < 1.04 mmol/L.
- •Patients were aged 25 to 65 years, with no restrictions on number of males or females.
- •Patients exhibited a long-term sedentary lifestyle and did not carry out moderate-intensity physical activity for at least three d/week of 30 min/d duration within three months of the study.
- •Patients were willing to participate and sign the informed consent form.
排除标准
- •Patients in an acute phase of various diseases or with organ failure, tumor, myocardial infarction, cardiac insufficiency, myocarditis, or chronic lung disease;
- •Patients with long-term alcohol consumption and those unable to ensure regular lifestyle habits during the intervention period;
- •Patients who were unable to ensure that they would carry out the stipulated exercise protocol during the intervention; and
- •Patients with drug modifications during the intervention that could affect the outcome markers.
研究组 & 干预措施
the maximum physiological value standardized group
Experimental
干预措施: the maximum physiological value standardized group (Behavioral)
the ventilatory threshold individualized group
Active Comparator
干预措施: the ventilatory threshold individualized group (Behavioral)
结局指标
主要结局
Peak oxygen uptake
时间窗: From enrollment to the end of 12 weeks of treatment
次要结局
未报告次要终点
研究者
Liu Ruojiang
Chief Therapist
Taiyuan Central Hospital of Shanxi Medical University
研究点 (1)
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