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临床试验/NCT03312920
NCT03312920撤回不适用

Investigating Memory Retrieval Improvement in Healthy Subjects

The University of Texas at Dallas1 个研究点 分布在 1 个国家目标入组 56 人开始时间: 2017年9月27日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
撤回
入组人数
56
试验地点
1
主要终点
Associative Memory assessed by a Face Name Associate Memory experiment

研究概览

简要总结

The purpose of this study is to investigate whether learning can be accelerated and associative memory performance improved in healthy subjects by applying transcranial Direct Current Stimulation (tDCS) during a Face Name memory task.

详细描述

Associative memory refers to remembering the association between two items, such as a face and a name or a word in English and the same word in another language. It is not only important for learning, but it is also one of the first aspects of memory performance that is impacted by aging and by Alzheimer׳s disease. For decades, neuroscientists have investigated associative learning and memory and ways to accelerate and enhance associative learning and memory.

Transcranial Direct Current stimulation (tDCS) is a non-invasive and painless electrical stimulation technique that has demonstrated to accelerate learning and improve memory in some studies. To investigate whether learning can be accelerated and associative memory improved by using tDCS, this study will compare the performance in a Face Name Associate memory task from 3 groups. The first group will get active aodal tDCS during the study phase of the Face Name Memory task, whereas the second group will get sham tDCS during the study phase of the task and the third group will get active cathodal tDCS.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Basic Science
盲法
Double (Participant, Outcomes Assessor)

入排标准

年龄范围
18 Years 至 35 Years(Adult)
性别
All
接受健康志愿者
是

入选标准

  • •Age: 18-35 years Native English Speaker

排除标准

  • •History of severe head injuries, epileptic insults, or heart disease. Severe psychiatric disorders and severe untreated medical problems. Contraindications for tDCS (pregnant women, implanted devices)

研究组 & 干预措施

active anodal tDCS

Experimental

active anodal tDCS with Face Name associate Memory task

干预措施: active anodal tDCS (Device)

Sham tDCS

Sham Comparator

sham tDCS with Face Name associate Memory task

干预措施: sham tDCS (Device)

active cathodal tDCS

Experimental

active cathodal tDCS with Face Name associate Memory task

干预措施: active cathodal tDCS (Device)

结局指标

主要结局

Associative Memory assessed by a Face Name Associate Memory experiment

时间窗: Associate Memory is assessed after a 10 minutes break following the study phase

Changes in performance in the Face Name Associate memory task is compared between the 2 groups (1. Real tDCS+ Face Name Associate memory task \& 2. Sham tDCS+ Face Name Associate memory task) to investigate the influence of tDCS on Associative Memory.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Sven Vanneste

Associate professor

The University of Texas at Dallas

研究点 (1)

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