Plasma metabolomics and proteomics profiling in subjects with low-grade inflammation given a dietary lipid challenge: A case of modulation with a traditional herb (Angelica keiskei)

Ewha Womans University0 个研究点目标入组 30 人开始时间: 待定最近更新: 2019年3月11日

适应症

试验速览

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•1) Subject who voluntarily agrees to participate and sign in informed consent form
•2) Subject who can participate all visits after rondomization
•3) Age: 20 years = Age = 65 years
•4) BMI (Body Mass Index): = 25 kg/m2
•5) CRP (C-reactive protein): 1.0 - 8.1 mg/L

•1) Continuous consumption of dietary supplement or oriental medicine or drug that affect inflammation, antioxidative capacity and lipid metabolism within 4 weeks before the first visit
•2)Current consumption of anticoagulant within 4 weeks before the first visit
•3)Following diseases :
•Chronic inflammatory disease, diabetes, liver dysfunction, renal dysfunction, cardiovascular diseases (hypertension, stroke, etc.), thyroid diseases, etc.
•4)Decrease of more than 4 kg body weight within 4 weeks before the first visit
•(weight-loss therapy)
•5)Excessive exercise (= 7 hours / week)
•6)Smoking = 10 cigarettes / day
•7)Alcohol consumption 140g / week
•8) Subjects with hypersensitivity to test materials
•9) Participation in other human study within 4 weeks before the first visit
•10) Pregnant or lactating women
•11) Any condition that the principal investigator believes may put the subjects at undue risk

发起方