Aerobic Interval Training Reduces and Compensates Age Related Decline in Cardiac Function
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 45
- 试验地点
- 2
- 主要终点
- Improvement of left and right ventricular early diastolic tissue velocity at rest and sub maximal exercise ,e'.
研究概览
简要总结
The purpose of this study is to determine the effect of aerobic interval training on left- and right ventricular diastolic- and systolic function on healthy, sedate people over 70 years. The old sedate cohort will be compared to young, sedate subjects also performing aerobic interval training and old master athletes without intervention.
详细描述
Aging is associated with a reduced diastolic and systolic function of the heart. Earlier studies have shown that physical exercise can improve both systolic and diastolic function. However the impact on age-related cardiac function is to some extent conflicting. The use of different training intensities will impact on the cardiac result. We have in earlier studies shown aerobic interval training at 90 % of maximal heart rate (4x4 minutes) to have more impact on cardiac function, endothelial function and maximal oxygen uptake compared to moderate intensity.
To our knowledge the effect of aerobic interval training on cardiac function has not been studied in an old, sedate group before.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 70 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •over 70 years, healthy
- •not exercising more than twice per week
排除标准
- •chronic illness
- •chronic use of any medication
- •regular smoking
- •metabolic or cardiovascular diseases
结局指标
主要结局
Improvement of left and right ventricular early diastolic tissue velocity at rest and sub maximal exercise ,e'.
时间窗: 12 weeks
次要结局
- Improvement of left and right ventricular systolic tissue velocity function at rest and sub maximal exercise, S'.(12weeks)