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临床试验/NCT03910816
NCT03910816已完成不适用

Hemorrhagic Risk and Transfusion Practice Evaluation in Elective Head, Neck and Spine Surgery.

University Hospital, Montpellier1 个研究点 分布在 1 个国家目标入组 377 人开始时间: 2015年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
377
试验地点
1
主要终点
Transfusion rate for each surgical procedure

研究概览

简要总结

During elective surgery, the decision to transfuse a patient to correct anemia or an unstable hemodynamic state is often determined on a case by case basis according to personal and hospital transfusion practice. There is wide variability in these practices. Literature suggests that a restrictive transfusion practice is equivalent, if not better, than a liberal practice in terms of morbidity and mortality. However, these data may not be generalizable to specific head, neck, and spine surgeries.

At the head and neck department of Montpellier University Hospital, the hemorrhagic risk has not been precisely measured for certain surgical procedures. Thus hemorrhagic risk tends to be overestimated and unnecessary blood tests tend to be ordered.

In our single center, retrospective, observational study the investigators will determine the hemorrhagic risk related to each elective surgical procedure performed in our center. The investigators will also analyze the transfusion triggers used, and will compare them to national and international recommendations. The results of this study will inform transfusion and laboratory practice for patients undergoing head, neck, or spine surgery.

详细描述

Our single center, retrospective, observational study will analyze the transfusion practices at the Montpellier University Hospital during the perioperative period (defined as 24 hours before surgery to 48 hours after surgery).

Aim of the study The aim of the study is to identify the transfusion rate for each surgical procedure (transfused patients / total number of procedures performed).

The study will also allow us:

  • to identify the hemorrhagic risk related to each surgical procedure performed;
  • to define the triggers for and factors determining transfusions of PRBC and others bloods products, according to the surgical procedure and to the patient's caracteristicus;
  • to assessee the quality of transfusion practices according to the national and international recommendations;
  • to evaluate the accuracy of the preoperative bleeding risk estimation;
  • to check the traceability of the transfusions in our department;
  • to evaluate the length of hospital stay (LOS) and the 30-days outcome of transfused patients

Starting from these objectives, a model of transfusion management could be defined.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • scheduled surgery between 1st Jan 2015 and 31st Dec 2017
  • age > 18

排除标准

  • Emergency surgery
  • Age < 18

结局指标

主要结局

Transfusion rate for each surgical procedure

时间窗: 24 hours before surgery to 48 hours after surgery

transfused patients / total number of procedures performed

次要结局

  • hemorrhagic risk(1 day)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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