跳至主要内容
临床试验/NCT03707691
NCT03707691招募中不适用

Pitch Perception and Memory: Deficits and Training

Hospices Civils de Lyon1 个研究点 分布在 1 个国家目标入组 960 人开始时间: 2019年11月26日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
招募中
入组人数
960
试验地点
1
主要终点
percentages of correct responses in listening tests

研究概览

简要总结

Pitch perception and memory are central in auditory cognition, in particular for sound source segregation and recognition, speech prosody and music processing. Here the investigator assess pitch perception and memory in hearing-impaired listeners wearing cochlear implant(s) and listeners with congenital amusia, both compared with control listeners. Behavioral, EEG, and MEG measures are collected in audio and audio-visual contexts to characterize pitch processing deficits, and test a pitch training program.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Basic Science
盲法
None

入排标准

年龄范围
5 Years 至 90 Years(Child, Adult, Older Adult)
性别
All
接受健康志愿者
是

入选标准

  • •For adult participants:
  • •Aged between 18 and 90
  • •Absence of neurological and psychiatric disorders
  • •No major cognitive deficit, ability to understand and apply study instructions
  • •Motivation to participate efficiently in the study
  • •Written informed consent to participant in the study
  • •Affiliated to social security
  • •Control participants and participants with congenital amusia for Experiment 5: MRI/MEG compatibility
  • •For underage participants:
  • •Subject aged 5 years and over
  • •Informed consent of parents or guardians for the participation of the child being studied
  • •No neurological or psychiatric history
  • •Without major cognitive impairment and ability to understand and apply setpoint.
  • •Subject affiliated to a social security scheme
  • •Motivation to participate effectively in the project

排除标准

  • •For adult participants:
  • •Age below 18 or above 90
  • •Pregnant or breast-feeding woman
  • •For underage participants:
  • •- Pregnant or nursing minors

研究组 & 干预措施

Cochlear implant users

Experimental

In both arms a pitch training protocol and a visuo-spatial training protocol are applied.

干预措施: Listening tests. Pitch training protocol (Behavioral)

Cochlear implant users

Experimental

In both arms a pitch training protocol and a visuo-spatial training protocol are applied.

干预措施: visuo-spatial training protocol (Behavioral)

Cochlear implant users

Experimental

In both arms a pitch training protocol and a visuo-spatial training protocol are applied.

干预措施: EEG/MEG/MRI recordings. (Behavioral)

Participants with Congenital Amusia

Experimental

In both arms a pitch training protocol and a visuo-spatial training protocol are applied.

干预措施: Listening tests. Pitch training protocol (Behavioral)

Participants with Congenital Amusia

Experimental

In both arms a pitch training protocol and a visuo-spatial training protocol are applied.

干预措施: visuo-spatial training protocol (Behavioral)

Participants with Congenital Amusia

Experimental

In both arms a pitch training protocol and a visuo-spatial training protocol are applied.

干预措施: EEG/MEG/MRI recordings. (Behavioral)

Control Participants

Experimental

干预措施: Listening tests. Pitch training protocol (Behavioral)

Control Participants

Experimental

干预措施: visuo-spatial training protocol (Behavioral)

Control Participants

Experimental

干预措施: EEG/MEG/MRI recordings. (Behavioral)

结局指标

主要结局

percentages of correct responses in listening tests

时间窗: during procedure

reaction times in listening tests

时间窗: during procedure

Event-Related Fields

时间窗: during procedure

MEG measurements

Oscillations

时间窗: during procedure

MEG measurements

次要结局

  • Event-Related Fields(Day 0)
  • percentages of correct responses(Day 0)
  • reaction times(Day 0)
  • Oscillations(Day 0)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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