Postoperative Pain in Patients With Symptomatic Irreversible Pulpitis After Using Dexamethasone in Combination With Local Anesthesia by Two Different Techniques (Randomized Clinical Trial)
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 66
- 试验地点
- 1
- 主要终点
- visual analogue score (VAS) from 0 to 10
研究概览
简要总结
The aim of this randomized clinical trial to evaluate the effect of dexamethasone in two different techniques on postoperative pain by dividing patients randomly into three groups:
- Group I: buccinator injection of dexamethasone.
- Group II: buccal infiltration of dexamethasone.
- Group III (Control): IANB using local anesthesia only post operative pain will be evaluated subjectively by patients by VAS score after procedure immediately and follow up for 12, 24 and 72 hours and frequency of analgesic intake
详细描述
the previous studies used dexamethasone with LA to prolong the duration of nerve block , Dexamethasone is used in reducing intraoperative endodontic pain the study main aim is to overcome the problem of severe postoperative pain after endodontic treatment in patients with acute irreversible pulpitis by evaluating the effect of dexamethasone in two different techniques by giving dexamethasone injection of buccinator muscle, or dexamethasone as buccal infiltration, and comparing the results with inferior alveolar nerve block using local anesthesia only. pain score evaluated using VAS score preoperatively and postoperatively with different anesthetic techniques after endodontic treatment.and their effet on frequency of analgesic intake
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Both genders
- •Older than age of (18 to 60) years
- •Participants willing to commit for the entire period of the trial and agreed to sign the written consent after full explanation of the study
- •Having a mandibular molar tooth with vital pulp
- •These patients were also suffering from symptomatic irreversible pulpitis ,intermittent or continuous sharp pain that lasts longer after removal of the stimulus
- •Patients with moderate to severe symptoms VAS≥4
排除标准
- •Vulnerable group; pregnant females, mentally ill and diseased patientsetc.…
- •Patients irritable to local anesthesia
- •Patients who are supposed to take plain anesthesia
- •Use of analgesic or antibiotic within 6 hours before the visit
- •Absence of bleeding in the pulp chamber during cavity preparation
- •Severe periodontal disease b- Patients' randomization, allocation and blinding:
研究组 & 干预措施
control
no intervention
buccinator injected by DEX drug
patients will receive dexamethasone(2ml/8mg) 1ml per 30 sec slow injection at buccinator muscle as single injection preoperatively
干预措施: dexamethasone 8mg (Drug)
buccal infiltration by DEX drug
buccal infiltration of dexamethasone (8mg/2ml) as single injection preoperative
干预措施: dexamethasone 8mg (Drug)
结局指标
主要结局
visual analogue score (VAS) from 0 to 10
时间窗: postoperative 72 hours
VAS preoperative ,immediately postoperative,12hrs,24hrs,72hrs
次要结局
未报告次要终点
研究者
Salma Medhat
MSc Student
Ain Shams University