NCT01949623已完成不适用
Biomarkers In Retinitis Pigmentosa (BIRP)
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Aqueous levels of markers of oxidative stress in patients with RP and controls.
研究概览
简要总结
In this study, markers of oxidative stress will be measured in the aqueous humour and plasma of RP patients compared to controls.
详细描述
People with Retinitis Pigmentosa have loss of night vision followed by loss of central vision due to damage and death of photoreceptors. One of the mechanisms causing damage is high levels of oxygen in the eye. This damage produces specific biomarkers which can be measured. In this study, these biomarkers will be assessed in people with Retinitis Pigmentosa and compared to controls.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 100 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Signed informed consent and authorization of use and disclosure of protected health information
- •Age more than or equal to 18 years
- •For the study group, patients diagnosed with Retinitis Pigmentosa by the investigators
- •For the control group, patients undergoing vitreoretinal surgery for macular hole, epiretinal membrane, vitreomacular traction, retinal detachment, neovascular Age-related Macular Degeneration (AMD) and Diabetic Retinopathy will be eligible
排除标准
- •Patients with active or suspected ocular or periocular infection
结局指标
主要结局
Aqueous levels of markers of oxidative stress in patients with RP and controls.
时间窗: 2 years
次要结局
未报告次要终点
研究者
研究点 (1)
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