Prevalence of BK Viremia in Simultaneous Liver-Kidney Transplant Recipients: A Retrospective Single-Center Review
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- To characterize the prevalence of BKV in the SLK patient population at (Methodist Dallas Medical Center)MDMC.
研究概览
简要总结
The human BK polyomavirus is a significant risk factor for renal transplant dysfunction and allograft loss. The prevalence of BK viremia (BKV) following kidney transplantation is estimated to be 10-20%.
详细描述
The human BK polyomavirus is a significant risk factor for renal transplant dysfunction and allograft loss. The prevalence of BK viremia (BKV) following kidney transplantation is estimated to be 10-20%. Immunosuppression reduction is the management cornerstone for BKV and has been shown to be effective at clearing the virus while maintaining graft function in both kidney alone and simultaneous kidney-pancreas transplant recipients. However, there is a lack of published data on the prevalence and outcomes in simultaneous liver-kidney (SLK) transplant recipients.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 100 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 18 years or older
- •SLK recipients transplanted at MDMC between 2015-2020
排除标准
- •Below 18 years of age
- •Patients who did not undergo SLK transplant at MDMC
结局指标
主要结局
To characterize the prevalence of BKV in the SLK patient population at (Methodist Dallas Medical Center)MDMC.
时间窗: over a 6-year period (2015 to 2020).
number of SLK transplant recipients who were transplanted at (Methodist Dallas Medical Center)MDMC
次要结局
未报告次要终点