asal High Flow Versus Conventional Oxygen Therapy in Emergency Department Patients With Asthma Exacerbation and Hypoxemia: A Randomized Controlled Trial

Siriraj Hospital0 个研究点目标入组 50 人开始时间: 2018年9月26日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•1.Patients with age of 18 years or older
•2.Patients who previously diagnosed with asthma according to GINA guideline
•3.Patients who present with symptoms compatible with exacerbation according to GINA guideline (progressive increase in symptoms of shortness of breath, cough, wheezing or chest tightness and progressive decrease in lung function)
•4.Patients with hypoxemia defined as SpO2 at room air of less than 95%

•1.Patients with respiratory failure; defined as respiratory rate >35 breaths/min, SpO2 <90% despite oxygen supplement or signs of increased work of breathing, as observed by use of accessory muscles and abdominal asynchrony.
•2.Patients with hemodynamic compromise (blood pressure <90/60 mmHg) despite intravenous fluid resuscitation
•3.Patients with a Glasgow Coma Scale score less than 13
•4.Patients with contraindications to the use of equipment with positive airway pressure
•5.Patients previously diagnosed with COPD, lung cancer, myocardial infarction (within 3 months), renal insufficiency requiring hemodialysis
•6.Patients previously smoking > 5 pack/year
•7.Patients concurrently diagnosed with other lower airway conditions such as pneumonia, pulmonary edema
•8.Patients who decline to participate
•9.Pregnant patients

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