Effects of Total Intravenous Anesthesia With Propofol-remifentanil Versus Inhalational Anesthesia With Sevoflurane on Quality of Recovery in Patients Undergoing Transsphenoidal Surgery for Pituitary Tumor
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 82
- 试验地点
- 1
- 主要终点
- QoR-40 score
研究概览
简要总结
A number of studies have compared the effects of total intravenous anesthesia(TIVA) versus inhalational anesthesia on perioperative period during transsphenoidal surgery. However, they have limitations especially for the phase of recovery after anesthesia: a fragmentary assessment. Quality of Recovery 40 (QoR-40) questionnaire was multi-dimensionally designed to assess the degree of recovery, specially after anesthesia and surgery. In this study, the investigators aim to compare the quality of recovery after inhalational anesthesia and after TIVA through QoR-40 questionnaire in patients undergoing transsphenoidal surgery for pituitary tumor under general anesthesia.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 19 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients over age 19
- •Scheduled to undergo transsphenoidal surgery for pituitary tumor
- •ASA class I and II
排除标准
- •Left ventricular ejection fraction < 55%
- •Third-degree atrioventricular block
- •Second-degree atrioventricular block (P:QRS ratio of 3:1 or higher)
- •History of myocardial infarction, stroke or cardiac surgery within the previous 1 year
- •Severe neurological disease
- •Use of sedative, opioid or sleep-inducing drugs
- •Allergic history of any study drug
- •Pregnancy
研究组 & 干预措施
TIVA group
Anesthesia is maintained with propofol during surgery
干预措施: total intravenous anesthesia (TIVA) (Drug)
inhalation anesthesia group
Anesthesia is maintained with sevoflurane during surgery
干预措施: inhalation anesthesia group (Drug)
结局指标
主要结局
QoR-40 score
时间窗: 1 day
We compare the QoR-40 scores of two groups 1 day after the operation.
次要结局
未报告次要终点