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临床试验/NL-OMON50331
NL-OMON50331尚未招募不适用

Right ventricular contractile reserve and oxygen consumption in pulmonary arterial hypertension - RV contractile reserve and oxygen consumption in PAH

Vrije Universiteit Medisch Centrum0 个研究点目标入组 15 人开始时间: 待定最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
15

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

年龄范围
18 至 99(—)

入选标准

  • In order to be eligible to participate in this study, a subject must meet all
  • of the following criteria:
  • Age >18 years
  • Patients have to be diagnosed with idiopathic -, hereditary -, or drug- and
  • toxins induced PAH or chronic thrombo-embolic pulmonary hypertension (CTEPH)
  • conform ESC/ERS guidelines. PAH is diagnosed when the following criteria are
  • o Mean Pulmonary Artery Pressure (mPAP) >= 25 mmHg
  • o Pulmonary Arterial Wedge Pressure (PAWP) > 15 mmHg
  • o Other possible causes of PAH are excluded

排除标准

  • A potential subject who meets any of the following criteria will be excluded
  • from participation in this study:
  • <1 year since last participation in research that included nuclear imaging
  • Congenital heart disease
  • Left sided heart disease
  • Pulmonary Hypertension other than idiopathic -, hereditary -, or drug- and
  • toxins induced PAH or CTEPH
  • Known coronary artery disease
  • Pregnancy
  • Malignancies
  • Kidney failure
  • Anemia (Hb < 8.0)
  • Atrial fibrillation
  • Use of β-blockers or a-blockers
  • Use of ACE-inhibitors
  • Age > 70 years

研究者

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