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临床试验/NCT07534787
NCT07534787尚未招募不适用

Clinical and Radiographic Evaluation of Ridge Splitting With Simultaneous Implant Placement Covered With Concentrated Growth Factor Membranes in Narrow Alveolar Ridge (Case Series).

Cairo University2 个研究点 分布在 1 个国家目标入组 10 人开始时间: 2026年5月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
尚未招募
入组人数
10
试验地点
2
主要终点
Pain (VAS score)

研究概览

简要总结

This study aims to evaluate the tissue biotype and bone density around dental implants in patients with narrow alveolar ridge. Ridge splitting with simultaneous implant placement covered with concentrated growth factor (CGF) membranes will be performed. Clinical and radiographic evaluation will be done using periodontal probe and CBCT. Pain will also be assessed using visual analogue scale (VAS) during follow-up period.

详细描述

This study is a case series conducted at the outpatient clinic of the Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Cairo University. It aims to evaluate the tissue biotype and bone density around dental implants in adult patients with narrow alveolar ridge.

Alveolar ridge resorption and soft tissue shrinkage after tooth extraction represent a major problem affecting both aesthetics and function. Therefore, preserving alveolar bone and improving soft tissue conditions are essential for successful implant placement. The use of concentrated growth factor (CGF) membranes combined with ridge splitting and simultaneous implant placement may enhance healing, reduce postoperative pain, and improve tissue biotype and bone density.

All patients will undergo clinical and radiographic assessment before the procedure. Preoperative CBCT will be used for surgical planning. Tissue thickness will be measured using a periodontal probe. During surgery, ridge splitting will be performed followed by implant placement, and CGF membranes will be applied over the grafted area. Autologous bone chips will be used for augmentation.

Postoperative evaluation will include assessment of tissue biotype, bone density using CBCT, and pain using visual analogue scale (VAS). Follow-up will be carried out immediately after surgery and up to 4 months postoperatively.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Treatment
盲法
None

入排标准

年龄范围
18 Years 至 60 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Patients with narrow alveolar ridge indicated for implant placement Age between 20 and 50 years Good general health Patients with adequate oral hygiene

排除标准

  • Patients with systemic diseases affecting bone healing Smokers Pregnant or lactating females Patients with poor oral hygiene Patients with history of radiation therapy in the head and neck region

研究组 & 干预措施

Ridge Splitting with Simultaneous Implant Placement and CGF

Experimental

Patients with narrow alveolar ridge will undergo ridge splitting with simultaneous implant placement. Concentrated growth factor (CGF) membranes will be prepared from the patient's blood and placed over the grafted area. Autologous bone chips will be used for augmentation. Clinical and radiographic evaluation will be performed to assess tissue biotype, bone density, and pain during follow-up period.

干预措施: Ridge splitting (Procedure)

Ridge Splitting with Simultaneous Implant Placement and CGF

Experimental

Patients with narrow alveolar ridge will undergo ridge splitting with simultaneous implant placement. Concentrated growth factor (CGF) membranes will be prepared from the patient's blood and placed over the grafted area. Autologous bone chips will be used for augmentation. Clinical and radiographic evaluation will be performed to assess tissue biotype, bone density, and pain during follow-up period.

干预措施: Dental implant placement (Procedure)

Ridge Splitting with Simultaneous Implant Placement and CGF

Experimental

Patients with narrow alveolar ridge will undergo ridge splitting with simultaneous implant placement. Concentrated growth factor (CGF) membranes will be prepared from the patient's blood and placed over the grafted area. Autologous bone chips will be used for augmentation. Clinical and radiographic evaluation will be performed to assess tissue biotype, bone density, and pain during follow-up period.

干预措施: Concentrated Growth Factor (CGF) (Biological)

结局指标

主要结局

Pain (VAS score)

时间窗: 1st day and 3rd day postoperative

Pain will be assessed using Visual Analogue Scale (VAS) ranging from 0 to 10.

次要结局

  • Tissue biotype thickness(Immediately postoperative and after 4 months)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Tasneem farrag abdelkader ayoup

Master's degree student, Oral and Maxillofacial Surgery, Faculty of Dentistry, Cairo University

Cairo University

研究点 (2)

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