NCT06733740招募中不适用
The Clinical Outcomes of Ultrasound-guided Thermal Ablation for the Treatment of Papillary Thyroid Carcinoma: A Multicenter Study
Chinese PLA General Hospital1 个研究点 分布在 1 个国家目标入组 3,000 人开始时间: 2024年12月10日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 3,000
- 试验地点
- 1
- 主要终点
- rate of disease progression
研究概览
简要总结
To evaluate long-term outcomes of ultrasound-guided thermal ablation for the treatment of papillary thyroid carcinoma
详细描述
To evaluate and predict long-term clinical outcomes of ultrasound-guided thermal ablation for the treatment of papillary thyroid carcinoma by a multicenter study
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients age between 18 and 80 year old, both sex
- •papillary thyroid carcinoma confirmed by core-needle biopsy or fine-needle aspiration
- •the largest diameter ≤2.0 cm
- •no clinical or imaging evidences of extrathyroidal extension, lymph node metastasis and distant metastasis on ultrasound, neck and chest CT
- •follow-up period ≥12 months
排除标准
- •patients with convincing evidence of aggressive papillary thyroid carcinoma or other type of thyroid cancer by biopsy
- •history of neck radiation
- •coagulation disorder, serious heart, respiratory, liver, or renal failure
- •dysfunction of the vocal cord on the opposite side
结局指标
主要结局
rate of disease progression
时间窗: through study completion, an average of 6 months
cervical lymph node metastases, recurrent tumors and persistent tumors confirmed by pathology
次要结局
- Rate of complications(1 week)
- rate of delayed surgery(through study completion, an average of 1 year)
- Rate of tumor disappearance(through study completion, an average of 6 months)
- Rate of volume reduction(through study completion, an average of 6 months)
- rate of change of thyroid function(through study completion, an average of 6 months)
研究者
Yu-kun Luo
Clinical Professor
Chinese PLA General Hospital
研究点 (1)
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