跳至主要内容
临床试验/NCT03430258
NCT03430258Unknown不适用

High-flow Nasal Cannula Oxygen Therapy With the Chest Trauma Patients

Second Affiliated Hospital, School of Medicine, Zhejiang University0 个研究点目标入组 90 人开始时间: 2018年3月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
发起方
入组人数
90
主要终点
compare the effectiveness of high-flow nasal cannula with conventional oxygen therapy in ICU patients with blunt thoracic injury.

研究概览

简要总结

This prospective randomized controlled study was conducted in the emergency intensive care units (EICU) of the second affiliated hospital Zhejiang university school of medicine, a large tertiary university hospital in HangZhou, China.The aim of this randomized study was to compare the effectiveness of high-flow nasal cannula with conventional oxygen therapy in ICU patients with blunt thoracic injury.

详细描述

This prospective randomized controlled study was conducted in the emergency intensive care units (EICU) of the second affiliated hospital Zhejiang university school of medicine, a large tertiary university hospital in HangZhou, China.The aim of this randomized study was to compare the effectiveness of high-flow nasal cannula with conventional oxygen therapy in ICU patients with blunt thoracic injury.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • The trauma registry was used to identify patients with moderate to severe blunt thoracic injury (abbreviated injury scale (AIS) chest score ≥3) admitted to the ICU

排除标准

  • had intubation and used the mechanical ventilation within 2 hours
  • had the emergency surgerys within 2 hours
  • patients can not accessed by transthoracic lung ultrasound because of the sever aerodermectasia or pneumothorax
  • the Glasgow Coma Scale <8

研究组 & 干预措施

conventional oxygen therapy

Placebo Comparator

oxygen was delivered by a nasal cannula or nonrebreather mask

干预措施: Conventional oxygen therapy (Device)

High-flow Nasal Cannula Oxygen Therapy

Active Comparator

High-flow Nasal Cannula Oxygen Therapy

干预措施: high-flow nasal cannula (Device)

结局指标

主要结局

compare the effectiveness of high-flow nasal cannula with conventional oxygen therapy in ICU patients with blunt thoracic injury.

时间窗: 72 hours

High-flow nasal cannula could reduce the intube rate of patients with blunt thoracic injury,and improve the the lung aeration for patients with thoracic injury

次要结局

  • number of days in ICU(7 days)

研究者

发起方
Second Affiliated Hospital, School of Medicine, Zhejiang University
申办方类型
Other
责任方
Sponsor

相似试验