NCT04750408Unknown不适用
Clinical Effects of Nasal High-flow Compared to Oxygen in Acute Viral Illness
Jens Bräunlich2 个研究点 分布在 1 个国家目标入组 52 人开始时间: 2021年1月22日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 52
- 试验地点
- 2
- 主要终点
- Rox index
研究概览
简要总结
The study compares oxygen and NHF in patients with acute viral illness. The duration will be 72h. After them physiological parameters and the outcome will be evaluated.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 100 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •acute hyperemic viral illness
- •acute hyperemic or hypercapnia respiratory failure
排除标准
- •intubation criteria
- •indication for NIV therapy
- •influences of primary endpoint (rip fracture, lung embolism)
- •tracheostomy
- •other interventional trials
- •noncompliance
结局指标
主要结局
Rox index
时间窗: 72 hours
(SpO2/FiO2)/RR = index without a unit, mean Rox-index in the two groups, comparison between the groups (significant differences), physiological parameter, to assess differences between the two groups
次要结局
- paCO2 in mmHg(72 hours)
- pH(72 hours)
- escalation of therapy(72 hours)
- paO2 in mmHg(72 hours)
研究者
Jens Bräunlich
Chair Pneumology and Respiratory Medicine
Klinikum Emden
研究点 (2)
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