A randomised control trial evaluating the effect of different trismus exercise regimens on adherence during radiation therapy for head and neck cancer

Chris O'Brien Lifehouse0 个研究点目标入组 93 人开始时间: 2023年12月18日最近更新: 2024年1月8日

适应症

试验速览

暂无简介。

•1. Diagnosis of oral, oropharyngeal (base of tongue or tonsil) or nasopharyngeal cancer
•2. Treatment involves radiotherapy in the definitive or adjuvant setting.
•3. Willingness to provide informed consent and willingness to participate and comply with the study requirements
•4. Able to complete questionnaires (with an interpreter/support person if necessary)
•5. Adults, 18 years and over

•1. Any participant who has non-union of the maxilla or mandible prior to commencing radiation (for example, if they had a jaw reconstruction which had not healed appropriately prior to radiation) or active osteoradionecrosis (ORN) (based on CT/X-RAY imaging after completing radiation). These conditions will be monitored by their treating surgeon at routine pre- and post-radiation review visits. Monitoring for non-union of the jaw after jaw surgery, and for signs of osteoradionecrosis after finishing radiation are routine practice/standard care. Signs include exposed bone, unmanaged pain or swelling, the managing radiation oncologist or surgeon would then recommend imaging within 1 week to investigate for non-union or ORN. If a patient is under investigation for non-union or ORN, they will be excluded from the trial.
•2. Participants who have a pre-existing condition that is contraindicative of resistance-based jaw stretching exercises, for example arthritis of the temporomandibular joint, unstable dentition or any other joint degradation condition effecting the temporomandibular joint.

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