Effect of moderate aerobic exercise with and without resistance on kidney function in chronic kidney disease.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 105
- 试验地点
- 1
- 主要终点
- 1. Blood urea and creatine
研究概览
简要总结
Aim:
Chronic renal disease is a serious condition that affects the kidney leds to various complications like high blood pressure, anemia, and general weakness and also effects the bones, nerves and heart. Aerobic exercise have various health benefit and prescribed for prevention and management of various diseases like diabetic mellitus, cardiovascular diseases, musculoskeletal problems, age related problems, cancer, etc. but the exercise prescription in the CKD patients are very minimal due the little understanding of the effect of exercise in this patients. Hence the aim of the study is to find effect aerobic exercises in renal functions of chronic renal disease.
Objective:
To find effect aerobic exercise in renal function of chronic kidney disease, functional capacity of CKD patients, fatigability level of CKD patients and Quality of life in CKD patients.
Methodology:
It’s an experimental design with comparative study ( pre and posttest ) in Out Patient Department of physiotherapy - ACS medical college and Hospitals, Study duration of 24 weeks. sample size of 35 / group ( total 105 for 3 groups) Subjects were Randomly assigned three groups.
Group 1 - Moderate intensity Continues walking and resisted exercise, for minimum 30 min/ day for 5 days a week with the intensity 12 to 14 Borg rating of perceived exertion.
Group 2 - Moderate intensity Continues walking for minimum 30 min / day for 5 days a week with Intensity 12 to 14 on Borg rating of perceived exertion
Group 3 - Conventional where no specific exercise will be prescribed.
Outcome:
Outcome measures are blood urea and creatine, Urine protein, 6 minute walk test, Fatigue Severity Scale and Kidney Disease Quality of Life Short Form
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 30.00 Year(s) 至 50.00 Year(s)（—）
- 性别
- All
入选标准
- •CKD patients with stage 3 and 4 on eGFR
- •Chronic kidney disease with age ranges from 30 to 50 years 3.Both genders
- •Medical clearance for exercise.
排除标准
- •Severe chronic kidney disease – stage 5
- •CKD caused other than diabetes and hypertension
- •Age over and above 50 years
- •Mentally unstable patients
- •Recent myocardial Infraction
- •COPD and Asthma
- •Any neurological conditions that restrict the mobility of the individuals
- •Recent fracture within six months in lower limb and upper limb
- •Severe OA knee, hip or ankle joint
- •Any type of carcinoma
- •Patient those who are physically active (doing moderate exercise).
结局指标
主要结局
1. Blood urea and creatine
时间窗: 24 weeks
2. Urine protein
时间窗: 24 weeks
次要结局
- 1. 6 minute walk test(2. Fatigue Severity Scale)
研究者
G VENUVENDHAN
Dr.MGR Educational and Research Institute