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临床试验/NCT03365258
NCT03365258Unknown不适用

The Effect of Applying Modified NUTRIC Scoring System to Evaluate the Nutrition Risk and Giving Different Types of Nutritional Support on Clinical Outcomes in Critically Ill Patients

Taichung Veterans General Hospital2 个研究点 分布在 1 个国家目标入组 150 人开始时间: 2017年12月28日最近更新:
适应症

试验速览

阶段
不适用
入组人数
150
试验地点
2
主要终点
In-hospital mortality

研究概览

简要总结

Malnutrition is very common in critically ill patients. It is quite important to evaluate nutritional status precisely. Heyland et al firstly reported NUTRIC score including age, APACHE II score, SOFA score, number of commorbidities, days from hospital to ICU admission and IL-6. Because the IL-6 is not routinely checked at ICU. A modified NUTRIC score without IL-6 is more practical. Previous studies showed lower in-hospital mortality in higher nutritional risk patients with higher caloric intake compared with lower caloric intake. However, there is still controversial regarding the in-hospital mortality between full caloric feeding and permissive underfeeding in critically ill patients. Herein the investigators conduct a study to investigate what kinds of nutritional supplements will decrease in-hospital mortality in different nutritional risk patients.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Other
盲法
None

入排标准

年龄范围
20 Years 至 100 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Medical intensive care unit patients
  • age elder than 20 years old
  • Intubated with ventilator support patients
  • Predicted ICU stay longer than 72 hours

排除标准

  • NPO patients
  • Contraindication for enteral feeding
  • Upper or lower GI bleeding patients
  • Feeding with gastrostomy or Jejunostomy patients
  • Metoclopramide related EPS or Torsades de pointes history

结局指标

主要结局

In-hospital mortality

时间窗: 90 days

mortality or discharge

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Wang, Chen-Yu

Director of Medical Intensive Care Unit

Taichung Veterans General Hospital

研究点 (2)

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