Effects of Noninvasive Brain Stimulation on Brain Activity and Appetite
试验速览
- 阶段
- 不适用
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Food craving assessed by the Food Cravings Questionnaire - State
研究概览
简要总结
The goal of this project is to identify brain mechanisms by which Noninvasive brain stimulation (NIBS) could decrease hyperphagia. The investigators will synchronously deliver NIBS and measure brain activity in a randomized, crossover, sham-controlled, fully blind study. This work will reveal brain mechanisms to reduce hyperphagia and may contribute to new therapeutic avenues to treat this eating disorder.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 20 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Hyperphagic
排除标准
- •Psychiatric disorders
- •Pregnancy
研究组 & 干预措施
Noninvasive brain stimulation: active
In active condition, subject will receive stimulation during all the duration of the experimental session.
干预措施: Noninvasive brain stimulation (Device)
Noninvasive brain stimulation: sham
In sham condition, subject will receive stimulation only at the beginning and at the end of the experimental session.
干预措施: Noninvasive brain stimulation (Device)
结局指标
主要结局
Food craving assessed by the Food Cravings Questionnaire - State
时间窗: 1 hour
次要结局
- Brain activity assessed by electroencephalography(1 hour)
- Brain activity assessed by blood-oxygen-level dependent contrast imaging(1 hour)