Impact of Caloric and Protein Adequacy on Postoperative Clinical Outcomes of Patients Undergoing Major Abdominal Surgery
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Postoperative complications
研究概览
简要总结
The role of nutritional therapy (TN) in the surgical patient is well described in the literature and is associated with reductions in postoperative complications, length of hospital stay, and mortality. Adequate determination of caloric and protein requirements is an essential step in the TN institution, avoiding hypoalimentation and hyperalimentation. Thus, it is essential to understand the changes in energy expenditure after surgery and its relation with nutritional status. In addition, little is known about the effect of nutritional therapy and caloric adequacy on parameters such as phase angle and dynamometry. Thus, the objective of this study is to evaluate the changes in energy expenditure after major abdominal surgeries and to evaluate the phase angle and dynamometry as possible markers of nutritional therapy. Energy expenditure will be assessed by indirect calorimetry. Functionality will be assessed by means of dynamometry and 6-minute walk test. Nutritional diagnosis will be given through subjective global assessment. Energy and protein intake will be monitored and registered daily. Phase angle will be obtained by performing bioelectrical impedance.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Over 18 years old
- •Patients admitted for major abdominal surgery
- •Sign the consent form
排除标准
- •Length of hospital stay less than 3 days
- •Pregnancy
- •Patients who, for any reason, can not perform indirect calorimetry
结局指标
主要结局
Postoperative complications
时间窗: 30 days after surgery
According to the Dindo-Clavien protocol
次要结局
- Phase angle(24 hours pre-surgery, 3 and 7 days after surgery)
- Body composition(24 hours pre-surgery, 3 and 7 days after surgery)
- Nutritional status(24 hours pre-surgery and 7 days after surgery)
- Functional status(24 hours pre-surgery, 3 and 7 days after surgery)
- Energy expenditure(3, 5 and 7 days after surgery)
研究者
Maria Isabel Toulson Davisson Correia
Professor/ Nutrition Service Coordinator
Federal University of Minas Gerais
