A Novel Therapeutic Approach for Controlling Complications Associated With Impacted Mandibular Third Molar Removal
试验速览
- 阶段
- 早期 1 期
- 状态
- 已完成
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Interincisal distance
研究概览
简要总结
Natural honey and dexamethason will be given before impaction removal then postoperative complications will be evaluated
详细描述
Patient with impacted lower third molar will be selected to this study agording to agent applied preoperative. Group 1 will receive topical honey and Group 2 will receive IV dexamethason. After surgical removal of impacted tooth under local anesthesia postoperative pain mouth opening, and swelling will be evaluated
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •impacted 3rd molar
- •healthy patient No smoking
排除标准
- •history of smoking Medical disease
研究组 & 干预措施
Control
No drug given before surgery
干预措施: Normal saline (Drug)
Dexamethason
Dexamethason will be given IV before surgery
干预措施: Dexamethasone (Drug)
Natural honey
Honey will be placed locally after impaction removal
干预措施: Honey (Drug)
Dexamethason and natural honey
Dexamethason will be given IV before surgery and Honey will be placed locally after impaction removal
干预措施: Dexamethasone and honey (Drug)
结局指标
主要结局
Interincisal distance
时间窗: 7th day postoperative
Distance between upper and lower teeth will be measured in mm by ruler
Edema
时间窗: 7th day postoperative
Measured from angle of mandible to angle of mouth in mm by ruler
次要结局
未报告次要终点
研究者
Alaa Altaweel
Associate professor
Al-Azhar University