NL-OMON55875已完成不适用
Clarifying the Vascular Aspects of Dementia - Vascular aspects in dementia
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 280
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Patients who attended the memory clinic of the Leiden University Medical
- •Center/ Bronovo/ Reinier de Graaf hospital within one year ago
- •Diagnosed with probable Alzheimer's disease
- •Diagnosed as Mild cognitive impairment
- •Diagnosed as Subjective cognitive impairment
- •Diagnosed as Vascular dementia
- •Capable of giving informed consent (see appendix)Control subjects
- •Healthy adults without memory complaints aged between 40-90 years old
排除标准
- •- Contra-indication to MRI scanning:
- •Claustrophobia
- •Pacemakers and defibrillators
- •Nerve stimulators
- •Intracranial clips
- •Intraorbital or intraocular metallic fragments
- •Cochlear implants
- •Ferromagnetic implants
- •Hydrocephaluspump
- •Intra-utrine device (not all types)
- •An iron wire behind the teeth
- •Permanent make-up
- •Tattoos above the shoulders (not all)- Specific contraindications to fMRI
- •Seizure within prior year.
- •Noncorrectable visual impairment.- MMSE < 19 points (measured at moment of
- •screening or at memory clinic with a maximum of 6 months in retrospect) (this
- •cutoff was also used in the Leiden 85-Plus study30)
- •- Severe physical restrictions (completely wheelchair dependent)
- •- Age above 90
研究者
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