Electrophysiological and Bioenergetic Study of Variations in Cognitive and Physical Performance in Healthy Humans: EEG Monitoring for PERFormance Anticipation
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 169
- 试验地点
- 2
- 主要终点
- Identify electrophysiological markers in humans depending on whether the experimental conditions induce cognitive fatigability.
研究概览
简要总结
Identify, characterize and then validate electrophysiological markers linking electrophysiological cerebral activity and performance in cognitive and physical fatigability in humans. To do this, noninvasive explorations of electroencephalography (EEG) and magnetoencephalography (MEG) will be carried out under two conditions of different experiments, the first one that induces a cognitive fatigability and the second one that induces physical fatigability.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- •Pregnant women, nursing mothers or those of childbearing age without contraception
- •Persons under guardianship, curatorship or any other administrative or judicial measure of deprivation of liberty or of liberty
- •Persons protected by the law
- •Persons who have performed a maximum stress test within 15 days of the date of inclusion,
- •In the course of drug treatments against indicated for the protocol (treatment for neurological diseases, psychiatric ...).
- •Metal implants incompatible with MRI (for the subjects concerned, see appendices)
- •Metallic implants incompatible with the MEG (for the subjects concerned, see appendices)
研究组 & 干预措施
Cognitive Fatigability
干预措施: Electroencephalography (EEG) multi-sensor (Other)
Cognitive Fatigability
干预措施: Magnetoencephalography (MEG) (Other)
Cognitive Fatigability
干预措施: Behavioral Measures (Other)
Cognitive Fatigability
干预措施: Reaction time measurement (Other)
Physical Fatigability
干预措施: Production of CO2 (VCO2) (Other)
Cognitive Fatigability
干预措施: Assessment of physical performance (Other)
Cognitive Fatigability
干预措施: Electrooculogram (EOG) (Other)
Cognitive Fatigability
干预措施: Electromyogram (EMG) (Other)
Cognitive Fatigability
干预措施: Electrocardiogram with 3 leads (Other)
Physical Fatigability
干预措施: Electroencephalography (EEG) multi-sensor (Other)
Physical Fatigability
干预措施: Magnetoencephalography (MEG) (Other)
Physical Fatigability
干预措施: Behavioral Measures (Other)
Physical Fatigability
干预措施: Reaction time measurement (Other)
Physical Fatigability
干预措施: Assessment of physical performance (Other)
Physical Fatigability
干预措施: Electrooculogram (EOG) (Other)
Physical Fatigability
干预措施: Electromyogram (EMG) (Other)
Physical Fatigability
干预措施: Electrocardiogram with 3 leads (Other)
Physical Fatigability
干预措施: Electrodermogram (EDG) (Other)
Physical Fatigability
干预措施: Consumption of O2 (VO2) (Other)
结局指标
主要结局
Identify electrophysiological markers in humans depending on whether the experimental conditions induce cognitive fatigability.
时间窗: 7 hours
The evaluation of cognitive performance will be carried out by means of conventional behavioral measures, of the press-button type, handling of a mouse or of a joystick and measurement of reaction time.
Identify electrophysiological markers in humans depending on whether the experimental conditions induce physical fatigability with EEG.
时间窗: 7 hours
Electrophysiological measurements of cerebral activity will be performed by multi-sensor electroencephalography (EEG).
Identify electrophysiological markers in humans depending on whether the experimental conditions induce physical fatigability with MEG.
时间窗: 7 hours
Electrophysiological measurements of cerebral activity will be carried out by magnetoencephalography (MEG)
次要结局
- Refine (locate at the level of the cortex), the origin of these physiological markers(7 hours)
- Distinguish between different time scales of performance(7 hours)