Randomized study of prochlorperazine for the prophylaxis of oxycodon induced nausea in patients with cancer related pain - Prophylaxis use of prochloroperazine

on-Profit Organization JORTC0 个研究点目标入组 80 人开始时间: 2013年10月10日最近更新: 2023年10月17日

适应症

试验速览

暂无简介。

•1) Patients in need of anti-emesis medication (roughly >= NRS 3) Anti-emesis medication: prochlorperazine, metoclopramide, itopride, Mosapride citrate hydrate, Sulpiride, steroid 2) Episode of vomiting within 48hrs before registration 3) Patients with dementia, delirium, depressed level of consciousness, communication disorder due to aphasia, dyslexia, dysarthria etc 4) Patients with severe infection 5) Hypercalcemia (adjusted Ca conc (Ca mg/dL +(4-Alb)>11mg/dL) 6) Patient with ileus 7) Symptomatic brain metastasis 8) Patients who are planned to start chemotherapy or radiation therapy in purpose for palliation cancer pain, before the improvement of cancer pain by this protocol treatment. 9) Comorbidity which treatments take priority over cancer treatment. 10) Increase, decrease, cessation of hyptonic, anti-anxiety agent (tricyclic or tetracyclic, anti depressant, SNRI, SSRI, etc), psychotropic agent, anticonvulsant agent, ketamine hydrochloride) within 24hrs before registration 11) Patients taking adrenalin 12) Patients who are suspicious of sub-cortex brain disorder 13) Patients taking anticholinergic agent, triazole antifungal antibiotics 14) Patient who were judged to be ineligible by the doctor

发起方

on-Profit Organization JORTC