NCT06895941撤回不适用
Predictive Value of PET/CT for Efficacy of Neoadjuvant Immunotherapy in Non-small Cell Lung Cancer
Shanghai Pulmonary Hospital, Shanghai, China2 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2025年4月30日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 发起方
- 入组人数
- 100
- 试验地点
- 2
- 主要终点
- FAPI PET/CT predicts efficacy
研究概览
简要总结
The aim of this study was to investigate the enhancement of FAPI PET/CT metabolic parameters in predicting the efficacy performance of neoadjuvant immunotherapy using the pCR status of surgically resected specimens of lung cancer as the gold standard.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •(1) aged 18 years or older; (2) pathological diagnosis of non-small cell lung cancer; (3) lesions resectable by surgery; (4) no EGFR mutation or ALK mutation; (5) eligible for indications of neoadjuvant immunotherapy for lung cancer.
排除标准
- •(1) patients who had used any other antitumor drugs or radiotherapy; (2) comorbidities with other malignant neoplastic diseases or severe cardiovascular diseases; (3) uncontrollable diabetes mellitus or fasting blood glucose level higher than 11 mmol/L on the test day; (4) pregnancy or recent pregnancy plan; (5) distant metastasis.
结局指标
主要结局
FAPI PET/CT predicts efficacy
时间窗: 2025.3.1-2027.3.1
AUC predicted by FAPI PET/CT for neoadjuvant immunotherapy in lung cancer.
次要结局
未报告次要终点
研究者
Chang Chen
Chief Physician
Shanghai Pulmonary Hospital, Shanghai, China
研究点 (2)
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