ACTRN12612000618853已完成未知
Incretin release, gastric emptying, postprandial glycaemia in cystic fibrosis with and without enzyme supplementation.
Adelaide University0 个研究点目标入组 32 人开始时间: 2012年6月8日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 32
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 10 Years 至 18 Years（—）
- 性别
- All
入选标准
- •16 subjects with cystic fibrosis (CF) with exocrine pancreatic insufficiency and taking pancreatic enzymes. CF related diabetes will be defined as those with diabetes detected on an oral glucose tolerance test (WHO definition); CF without diabetes will be defined as those with a normal glucose tolerance test in the previous 12 months.
- •16 healthy control subjects without clinically significant systemic disease, and BMI <95th centile will be recruited and will be matched for age to the CF subjects.
排除标准
- •Exclusion criteria CF subjects: severe pulmonary disease (FEV1<30% predicted), significant liver disease (Child-Pugh score >6), previous gastrointestinal surgery (apart from uncomplicated appendicectomy), requirement for medications that could affect gastrointestinal motility (eg erythromycin, SSRIs), pregnancy or lactation
- •Exclusion criteria controls: previous gastrointestinal surgery (apart from uncomplicated appendicectomy), requirement for medications that could affect gastrointestinal motility (eg erythromycin, SSRIs), pregnancy or lactation.
研究者
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