NCT04046861已完成不适用
"Influence of High Vitamin C Dose on Lactate During Extracorporeal Circulation for Heart Surgery and During the 24 Hours Thereafter." (double Blind Prospective Randomised Study)
University Medical Centre Maribor2 个研究点 分布在 1 个国家目标入组 70 人开始时间: 2023年3月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 70
- 试验地点
- 2
- 主要终点
- Concentration of lactate
研究概览
简要总结
The aim of our study is to find out whether high doses of vitamin C before cardiopulmonary bypass and during the first 24 hours after that have and impact of lowering the incidence of hyperlactatemia.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Triple (Participant, Care Provider, Investigator)
入排标准
- 年龄范围
- 18 Years 至 100 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •> 18 years old patients with cardiac disease needing surgery (coronary bypass, valve replacement)
排除标准
- •kidney stones
- •haemochromatosis
- •thalassemias
- •G-6-P deficiency
结局指标
主要结局
Concentration of lactate
时间窗: up to 30 hours
Measuring the concentration of lactate before cardiopulmonary bypass, after aortic clamp removal, at ICU admission,then every 6 hours
次要结局
- dose of noradrenaline and other vasopressors(up to 36 hours)
研究者
Andreja Möller Petrun, MD, PhD
MD, PhD, Assistant professor
University Medical Centre Maribor
研究点 (2)
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