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临床试验/NCT03440645
NCT03440645已完成不适用

Cardiovascular Screening for Family Members of People With Acute Coronary Disease: A Patient-Initiated and Family-Oriented Strategy

Lady Davis Institute2 个研究点 分布在 1 个国家目标入组 185 人开始时间: 2018年1月9日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
185
试验地点
2
主要终点
Change in mean modified Framingham cardiovascular risk score from the initial visit to the 6 month follow-up visit

研究概览

简要总结

Over a 12-month period, patients admitted with acute coronary disease to the cardiovascular care unit at the Jewish General Hospital (JGH), an academic tertiary care referral center in Montreal, Quebec, will be approached to refer first-degree relatives and/or household members age 18 years or older to an outpatient cardiovascular (CV) risk factor screening and treatment program. Relatives and household members will undergo a focused history, physical, and CV risk factor assessment and will receive evidence-based guideline-recommended treatment as indicated. Participants will be referred to nutritionists, smoking cessation programs, and to other allied healthcare professionals as needed. A follow-up visit at 6-months will assess treatment adherence and improvement in CV risk factors. All family and/or household members including the index patient will be encouraged to attend all healthcare visits together.

The effectiveness of the screening strategy will be measured by the total number of participants identified as intermediate or high modified Framingham 10-year risk of cardiovascular disease. The effectiveness of the primary prevention intervention will be measured by the change in percentage of the mean modified Framingham 10-year risk score for participants between the initial visit and 6-month follow-up. The value of the referral, screening, and treatment program, as well as participant engagement and satisfaction will also be systematically evaluated.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Prevention
盲法
None

入排标准

年龄范围
18 Years 至 70 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patient age ≤70 years old admitted with an initial diagnosis of an acute coronary event (such as acute coronary syndrome or myocardial infarction)
  • At least 1 first-degree family or household member age ≥ 18 years old

排除标准

  • No eligible family or household members
  • Inability to contact family or household members
  • Distance to study centre too far as determined by the patient
  • Family or household members who have been screened for CV disease in the previous 2 years.
  • Family or household members with known coronary disease.

结局指标

主要结局

Change in mean modified Framingham cardiovascular risk score from the initial visit to the 6 month follow-up visit

时间窗: 6 months

The change in percentage of the mean modified Framingham cardiovascular risk score for family and household members between the initial visit and the 6-month follow-up visit

次要结局

  • Effectiveness of the screening strategy(12 months of study recruitment)

研究者

发起方
Lady Davis Institute
申办方类型
Other
责任方
Principal Investigator
主要研究者

Michael Goldfarb

Clinician-Investigator

Lady Davis Institute

研究点 (2)

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