The Effectiveness of Perioperative Parecoxib Intravenous Administration in the Surgical Fixation of Unstable Ankle Fracture: A Prospective, Double-Blinded, Randomized, Placebo-Controlled Trial.

American Orthopaedic Foot & Ankle Society0 个研究点目标入组 40 人开始时间: 2021年4月16日最近更新: 2024年8月19日

适应症

试验速览

阶段: 3 期
状态: 已完成
发起方
入组人数: 40

研究概览入排标准研究者记录与标识符相似试验

研究概览

简要总结

Perioperative administration of parecoxib could not significantly provide better postoperative pain control and lower amount of opioid requirement than placebo. Single benefit of perioperative use of parecoxib seemed to be shorter length of hospital stay than placebo.

研究设计

研究类型: Interventional

入排标准

年龄范围: 18 Years 至 100 Years（—）
性别: All

入选标准

•The patient with unstable ankle fracture who had the indication for open reduction and internal fixation.

排除标准

•The contraindication of parecoxib use (1 pateint), thrombocytopenia on preoperative blood work (1 patient), head injury with contraindication for spinal anesthesia (1 patient), and acute on chronic fracture (1 patient).

研究者

发起方

American Orthopaedic Foot & Ankle Society

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