ISRCTN13797354已完成2 期
Imaging cerebral neuro-inflammation in acute and chronic cerebrovascular disease: a predictor of outcome and biomarker for guiding treatment (IN-CVD)
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 10
研究概览
简要总结
2020 results in https://pubmed.ncbi.nlm.nih.gov/32023020/ (added 10/05/2021)
研究设计
- 研究类型
- Observational
入排标准
- 性别
- All
入选标准
- •1. Ischemic stroke in middle cerebral artery territory
- •2. Mild to moderate severity (Modified Rankin Scale score 2 or 3)
排除标准
- •1. Neurological diagnosis of neurodegenerative disease
- •2. Inability to understand study information and/or express willingness to consent to the study due to communication difficulties (patients that wish to consent but are unable to sign or mark the consent form due to mobility issues may give their consent orally in the presence of at least one witness, who must sign the consent form as evidence that the information was accurately explained to and understood by the subject and that consent was freely given)
- •3. History of brain surgery, brain tumour, neuroinflammatory or neurodegenerative disease
- •4. Severe uncontrolled systemic illness
- •5. Patients in whom carotid endarterectomy/carotid stenting is due to be carried out within three months of recruitment to the study
- •6. Treatment with other drugs known to influence microglial activation, e.g. minocycline or cortical steroids (2 weeks prior to date of stroke)
- •7. Pregnancy
- •8. Contraindications to MRI scanning
研究者
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