Peritoneal Dialysis Daily Versus Six Days Per Week
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 入组人数
- 20
- 主要终点
- Patient's preference for treatment regimen
研究概览
简要总结
The study will enroll patients receiving daily peritoneal dialysis who have significant residual native kidney function. The investiators will visit the patients at a routinely scheduled clinic visit and again at a non-routine visit after the patients skip a single day of dialysis. Blood samples will be obtained and a quality of life questionnaire will be administered at both visits.
The primary aim will be to determine whether the patients would prefer daily treatment or being allowed to skip one day per week.
Other aims will be to determine the effect of skipping a day on plasma levels of urea nitrogen and creatinine.
详细描述
The patients' preference will be assessed by asking the simple question would you prefer to perform peritoneal dialysis daily of six days per week.
The quality of life questionnaire to be used will be the Dialysis Symptom Index (DSI) which has a range of 0 to 150 with a high score reflecting worse quality of life.
The chemical to be measured will be the plasma urea nitrogen in mg/dl and the plasma creatinine in mg/dl as measured by the clinical laboratory.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Sequential
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Daily treament with peritoneal dialysis and residual native kidney funciton with residual urea clearance greater than 2 ml/min.
排除标准
- •less than 3 months on peritoneal dialysis
- •recent change in the dialysis prescriptoin
- •recent peritonitis
结局指标
主要结局
Patient's preference for treatment regimen
时间窗: Two weeks per patient
Patient's stated preference for dialysis daily versus six days per week
次要结局
- Plasma solute levels(Two weeks per patient)
- Symptoms(Two weeks per patient)
研究者
Timothy Meyer
Professor
Stanford University